3 Cases of Latanoprost Associated Herpes Simplex Keratitis.

Kim, Ki Eon; Moon, Jung Il; Chung, Sung Kun; Baek, Nam Ho

Case Report

Journal of the Korean Ophthalmological Society 2002;43(6):1081-1085.
Published online June 1, 2002.

3 Cases of Latanoprost Associated Herpes Simplex Keratitis.

Ki Eon Kim, Jung Il Moon, Sung Kun Chung, Nam Ho Baek

Department of Ophthalmology, St. Mary 's Hospital, School of Medicine, The Catholic University of Korea, Seoul, Korea. eyedoc@cmc.cuk.ac.kr

Latanoprost 점안과 관련된 단순포진각막염 3례

김기언 ( Ki Eon Kim ) , 문정일 ( Jung Il Moon ) , 정성근 ( Sung Kun Chung ) , 백남호 ( Nam Ho Baek )

Abstract

PURPOSE
To report three cases in which herpes simplex keratitis developed after initiation of latanoprost. METHODS: We experienced three patients with herpes simplex keratitis after latanoprost instillation, two patients with open angle glaucoma and one is congenital glaucoma. We preformed herpes simplex virus culture for two cases. RESULTS: One patient with history of herpes simplex keratitis, resolution when latanoprost was stopped; antiviral therapy could not eradicate herpes simplex keratitis until latanoprost was discontinued. The second patient with latanoprost associated herpes simplex keratitis cleared with discontinuation of latanoprost and start of antiviral therapy. The third patient had resolution, only when latanoprost was stopped. The result of viral cultures for two cases was negative. CONCLUSIONS: Clinicians should be aware of development or recurrence of herpes simplex keratitis when laranoprost is used for intraocular pressure control.

Key Words: Herpes simplex keratitis;Latanoprost