Alkali Burns of the Cornea.

Youn, Dong Ho

Original Article

Journal of the Korean Ophthalmological Society 1972;13(2):59-62.
Published online January 1, 2001.

Alkali Burns of the Cornea.

Dong Ho Youn

Department of Ophthalmology, School of Medicine, Sectd National University, Seoul, Korea.

각막의 알카리화상에 관한 연구

Abstract

1. Alkali burns of rabbit corneas were produced by 5.0 N NaOH swabbing the cornea and surrounding sclera. 2. Collagenolytic activity of alkali burned corneas, and the effectiveness of collagenase inhibitors (0.2 M cysteine sol. and 0.5% zinc sulfate sol.) in preventing the perforation of corneas were studied by pathology. 3. In control group, almost 85% of coreas were perforated, but in treated group, no corneal perforations were found. 4. In control group, epithelial and endothelial thickenings are evident and no neovascularization could be seen, in treated group neovascularization is evident and slight cellular reactions were visualized.