| Animal Experiment for Comparison of Seoul Type Keratoprosthesis with Improved Biocompatibility and Conventional Keratoprosthesis. |
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E S Chung, H Y Kim, D G Choi, W R Wee, J H Lee |
1Dapartment of Ophthalmology, Samsung Medical Center, School of Medicine, Sungkyunkwan University.
2Department of Ophthalmology, College of Medicine, Seoul National University. |
| 생체적합성을 향상시킨 서울형인공각막과 기존인공각막의 동물실험 결과 비교 |
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정의상(Eui Sang Chung),김희영(Hee Young Kim),최동규(Dong Gyu Choi),위원량(Won Ryang Wee),이진학(Jin Hak Lee) |
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| Abstract |
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Keratoprosthesis implantation is the only method to improve vision in patients with poor success rate of penetrating keratoplasy. But due to high complication rate and short retention period, the success of keratoprosthesis has been limited. We designed this study to compare the clinical course of SKPro implanted rabbits with those of Worst type KPro and Legeais type KPro[Bio-KP(r)]. SKPro was retained well for 6-month follow up period without complications such like endophthalmitis, and retroprosthetic membrane in all three rabbits. But in rabbits implanted with Worst type KPro, two rabbits showed severe endophthalmitis during early postoperative period and the remaining rabbit also developed late endophthalmitis along with poor mechanical stability in pressure loading test. Legeais type KPro was implanted in only one rabbit and endophthalmitis was developed in early postoperative period. In conclusion SKPro showed a relatively superior clinical course after implantation in rabbits and this suggests the possibility of clinical application of SKPro in human cases. |
| Key Words:
Keratoprosthesis;Legeais type keratoprosthesis;Seoul type keratoprosthesis;Worst type keratoprosthesis |
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