Journal of the Korean Ophthalmological Society 2000;41(7):1585-1591.
Published online July 1, 2000.
The Complications of Botulinum Toxin Type A Chemodenervation in Strabismus.
Jae Sung Kim, Sueng Han Han, Helen Lew
Department of Ophthalmology, Youngdong Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea.
사시환자에서의 보투리눔 A 독소 화학절단술의 합병증 고찰
김재성(Jae Sung Kim),한승한(Sueng Han Han),유혜린(He Len Lew)
Abstract
We studied the safety and complication associated with treatment with botulinum A toxin chemodenervation. 70 eyes was entrolled and treated with botulinum A toxin chemodenervation. They were examed at 1 day, 1 week, 2 weeks, 1 month, 3 months and 6 months after the injection. Ptosis developed in 19 of 70 eyes(27.1%), but all of them recovered fully at 6 months after injection. A vertical deviation was noted in 19 eyes(27.1%), but all except one recovered fully at 6 months. Ptosis and vertical deviation developed more frequently in the group with the medial rectus muscle injection than with lateral rectus muscle injection. Subconjunctival he.morrhage and headache were also noted in 1 eye, respectively, but they disappeared at 4 weeks after the injection. Aggrevation of diplopia after injection was noted in 1 eye, which disappeared at 3 weeks after injection. Botulinum A toxin chemodenervation can be considered to be a safe method for the treatment of strabismus without the long-lasting serious complications.
Key Words: Botulinum toxin;Chemodenervation;Complication;Strabismus


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