The Effect of Apraclonidine Hydrochloride 0.5%Ve rsus 1%for Controlling Intraocular Pressure Elevation after Nd :YAG Laser Posterior Capsulotomy.

Nam, Ki Sun; Kim, Ki Young; Oh, Jin Seok; Lee, Kyung Wha

Original Article

Journal of the Korean Ophthalmological Society 2000;41(8):1760-1767.
Published online August 1, 2000.

The Effect of Apraclonidine Hydrochloride 0.5%Ve rsus 1%for Controlling Intraocular Pressure Elevation after Nd :YAG Laser Posterior Capsulotomy.

Ki Sun Nam, Ki Young Kim, Jin Seok Oh, Kyung Wha Lee

Department of Ophthalmology, Hangang Sacred Heart Hospital, The Hallym University Medical College.

야그레이저 후낭절개술시 안압상승에 대한 0.5% 와 1% Apraclonidine Hydrochloride 의 효과

남기선(Ki Sun Nam),김기영(Ki Young Kim),오진석(Jin Seok Oh),이경화(Kyung Wha Lee)

Abstract

Previous reports have shown that Nd:YAG laser capsulotomy is associated with elevated intraocular pressure(IOP). Topical apraclonidine hydrochloride has been shown to be effective in preventing postlaser pressure spikes. This study was designed to compare the effect of apraclonidine hydrochloride 0.5%versus 1% in controlling IOP elevation after Nd:YAG laser posterior capsulotomy. Fourteen eyes were treated with 0.5%apraclonidine(Group 1), twenty eyes with 1%apraclonidine(Group 2)and fifteen eyes without apra-clonidine(Group 3)in Nd:YAG laser posterior capsulotomy. The mean post-operative IOP at 1 to 3 hours of Group 3(15.0+/-3.6 mmHg, 16.0+/-4.3 mmHg) was higher than Group 1(10.8+/-3.5 mmHg, 11.6+/-3.0 mmHg)and Group 2 (11.2+/-3.0 mmHg, 12.7+/-2.3 mmHg)(P<0.05)and no statistically significant difference in mean IOP was found between Group 1 and Group 2(P>0.05). This result suggests that 0.5%and 1%apraclonidine are equally effective in preventing IOP rise and 0.5%apraclonidine can be a useful adjunct in preventing IOP elevation following Nd:YAG laser posterior capsulotomy.

Key Words: Apraclonidine hydrochloride 0.5%and 1%;IOP elevation;Nd:YAG laser posterior capsulotomy