Journal of the Korean Ophthalmological Society 1998;39(10):2393-2405.
Published online October 1, 1998.
Treatment and Prognosis of Retinoblastoma: Clinicopathologic Analysis of 101 Cases.
Joon Seok Song, Jae Kyung Lee, Tai Won Lee
Department of Ophthalmolohy, Korea Cancer Hospital, Seoul, Korea.
망막모세포종의 치료성적 및 예후인자에 관한 연구
송준석(Jun Suk Song),이재경(Jae Kyung Lee),이태원(Tai Won Lee)
Abstract
The clinicopathologic characteristics, treatments and prognosis of retinoblastoma, the most common intraocular tumor in children, were studied retrospectively in 101 cases(128eyes) who visited our clinic from 1987 to 1996. All patients were followed for 2 years or longer. Twenty seven cases were bilateral and seventy four cases were unilateral,. Eihgty four eyes were enucleated. Twenty one eyes were successfully treated by conservative modality. The rest refused any type of treatment. Orbital recurrence or distant metastasis were observed in 5 cases after enucleation without systemic treatment, and one died in spite of irradiation and aggressive chemotherapy. It is widely recognized that the prognosis for survival of retinoblastoma patients, especially unilateral, is excellent, however the authors emphasize the importance of careful postoperative histopathologic review and long term periodic follow-up to improve long-term prognosis.
Key Words: Intraocular tumor;Prognosis;Retinoblastoma;Treatment


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