| Peripapillary Atrophy: 1, Comparison of Normal Eyes and Eyes with Primary Open-Angle Glaucoma. |
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Ki Bang Uhm, Seoung Bock Lee, Ji Taek Kim, Chul Hong |
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Department of Ophthalmology, College of medicine, Hanyang University. |
| 정상안과 원발개방각녹내장안에서의 유두주위위축 |
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엄기방(Ki Bang Uhm),이승복(Seoung Bock Lee),김지택(Ji Taek Kim),홍철(Chul Hong) |
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| Abstract |
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To confirm the value of the peripapillary atrophy(PPA) for the diagnosis and follow-up of patients with glaucoma, we performed magnification-corrected morphometry of photographs of 234 eyes of 141 patients with primary open-angle glaucoma and 139 eyes of 86 normal subjects. For the data analysis, only one eye of each patient was randomly selected. Both groups did not differ significantly in age. refractive error and disc area. According to the neuroretinal rim/disc area ratio, the glaucoma group was divided into four stages(1; more than 0.61, 2; 0.60~0.41, 3; 0.40~0.21, 4; less than 0.20). PPA differentiated into two different zones(alpha and beta). Zone alpha(0.76+/-0.55mm2 vs 0.47+/-0.32mm2) and zone beta(0.50+/-0.63mm2 vs 0.06+/-0.15mm2) and the total PPA(1.26+/-0.97mm2 vs 0.54+/-0.38mm2) were significantly larger(p=0.0001), and zone beta occurred more often(59.5% vs 17.4%, P=0.0001) in the glaucoma group than in the normal group. The area, angular extent and width of both zones enlarged significantly with increasing stage of glaucoma. The frequency of zone beta increased with advancing stage of glaucoma. These findings suggest that both zone alpha and beta increase continuously with advancing neural rim damage. Therefore, the PPA is useful for the diagnosis and progression of glaucomatous nerve damage. |
| Key Words:
Peripapillary atrophy;Primary open-angle glaucoma;Zone alpha;Zone beta |
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