Clinical Aspects of Infectious Endogenous Endophthalmitis.

Sung, Kyung Rim; Lee, Yong Bum; Kim, Chang Hoon; Sohn, Joon Hong; Yoon, Young Hee

Original Article

Journal of the Korean Ophthalmological Society 1999;40(1):176-181.
Published online January 1, 1999.

Clinical Aspects of Infectious Endogenous Endophthalmitis.

Kyung Rim Sung, Yong Bum Lee, Chang Hoon Kim, Joon Hong Sohn, Young Hee Yoon

¹University of Ulsan, Asan Medical Center.
²Capital Army Hospital.

감염성 내인서 ddkssodua의 임상적 고찰

성경림(Kyung Rim Sung),이용범(Yong Bum Lee),김창훈(Chang Hoon Kim),손중훈(Joong Hoon Sohn),윤영희(Young Hee Yoon)

Abstract

Infectious endogenous endophthalmitis is a relatively rare, but seriously devasting disease. To evaluate clinical aspects of this disease, we performed a retreospective study on 7 eyes of 7 patients who had been treated with this diagnosis from July 1994 to January 1998 at Asan Medical Center. The preceding systemic diseases consisted of liver abscess, non-small cell lung cancer, spontaneous bacterial peritonitis, acute cholangitis, cystitis, systemic candidiasis. Microorganisms were recovered in blood culture in 4 of them(3 Klebsiella pneumoniae and one Candida albicans). One among these patients also revealed culture positive for Klebsiella pneumoniae in the vitreous as well as in his blood. All patients received intravitreal vancomycin and amikacin injection following vitreous and aqueous tapping. Four patients underwent pars plana vitrectomy as the second procedure and 2 of them expired. At the final follow up, retina remained attached succesjully in six of 7 eyes, yet the visual outcome was so poor that only two recovered over 5/200 or better. Infectious endogenous endophthalmitis has guarded prognosis since causative microorganisms are often extremely virulent, detection of this disease is likely to be delayed and appropriate management can not be started immediately. High index of suspicion for the diagnosis and the intensive treatment are strongly suggested to achieve the best result.

Key Words: Infectious endogenous endophthalmitis;Intravitreal antibiotics injection