Journal of the Korean Ophthalmological Society 1999;40(2):409-416.
Published online February 1, 1999.
Chanages of Central Corneal Endothelial Cells Following Phacoemulsification Through a Temporal Clear Corneal Incision under Topical Anesthesia.
Yeoun Sook Chun, Jin Hak Lee
Department of Ophthalmology, College of Medicine, Seoul National University.
점안마취 및 이측투명각막절개술을 이용한 백내장수술이 중심각막내피세포에 미치는 영향
전연숙(Yeoun Sook Chun),이진학(Jin Hak Lee)
Abstract
To evaluate the changes of the central corneal endothelial cell density and morphology after phacoemulsification and foldable silicone intraocular lens(IOL) implantation through a 3.2mm temporal clear corneal incision under topical anesthesia. On 43 patients(43 eyes) who had no systemic and ocular disease to influence the status of corneal endothelium , central corneal thickness, central corneal endothelial celldensity, pleomorphism index and polymegathism index, there was significant increase at 1 day postoperatively and recovery to preoperative state at 2 months poeroperatively. Central corneal endothelial cell losses were 8.92% at 1 day postoperatively and 15.95% at 2 months poeroperatively(p=0.00) and statistically significant increase of polymegathism index was noted at 1 day and 2 months poeroperatively. However no significant difference in central corneal endothelial cell loss and polymegathism index was noted at 6 months postoperatively. From the above results, we concluded that the phacoemulsification through a temporal clear corneal incision under topical anesthesia decreases the central corneal endothelial cell density and increase polymegathism index of the corneal endothelial cells, but these changes become stabilized after postoperative 2 months. Also proper control group must be set up to detect causes of corneal endothelial cell loss and it is neede to estalblish a new criteria for safe corneal endothelial cell density.
Key Words: Central corneal endothelial cell loss;Temporal clear corneal incision;Topical anesthesia


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