The Trend of Species and Microbial Susceptibility of Bacteria Isolated from the Anophthalmic Socket and Fellow Normal Conjunctiva. |
Tae Kon Yi, Sang Kyung Choi |
Department of Ophthalmology, Korea Veterans Hospital, Seoul, Korea. |
무안구안과 반대편 건안의 결막낭 세균총의 분포와 항균제에 대한 감수성의 추이 |
이태곤(Tae Kon Yi),최상경(Sang Kyung Choi) |
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Abstract |
In 189 consecutive non-inflamed anophthalmic patients wearing uniocular prosthesis, the conjunctival flora was evaluated and compared to that of the opposite healthy eye. And this results were compared with that of department of clinical pathology studied from January 1997 to July 1998. The incidence of bacterial isolation on the anophthalmic side (63.5%) was significantly higher than that on the healthy side (28.0%). Especially, the incidence of potential pathogenic bacterial isolation. (S.aureus, streptococci spp. and gram-negative bacilli grouped together) on the anophthalmic side (42.3%) was very significantly higher (p<0.001) than that on the healthy side (6.9%).The antimicrobial susceptibility to ciprofloxacin was high (>90%) in all bacterial isolate from the both anophthalmic socket and fellow normal conjunctiva. The bacteria isolated from the anophthalmic socket and fellow normal conjunctiva were similarly sensitive to vancomycin,clindamycin, gentamicin, imipenem, tobramycin, amikacin, netilmicin, colistin and were resistant to penicillin, ampicillin and tetracycline. No significant difference in the anophthalmic conjunctival flora between our study and the previous report but the antimicrobial susceptibility to clindamycin in coagulase-negative staphlyococcus (CNS) and S.aureus from the anophthalmic socket is higher than that of the previous report. The antimicrobial susceptibility to erythromycin in gram-positive bacteria except coagulase-negative staphlyococcus (CNS) and S.aureus from the anophthalmic socket is lower than that of the previous report. The species isolated from our study were more sensitive to the majority of antimicrobial agents than that of the microbial laboratory report. But,the antimicrobial susceptibilities of our study to chloramphenicol and colistin were very significantly lower than that of the microbial laboratory report (p<0.001). |
Key Words:
Anophthalmic conjunctiva;Antimicrobial susceptibility;Bacterial flora;Ocular prosthesis |
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