Journal of the Korean Ophthalmological Society 1999;40(10):2728-2734.
Published online October 1, 1999.
Endothelial Cell Change after Photorefractive Keratectomy and Laser In Situ Keratomileusis.
K S Kim, S H Baek
Department of Ophthalmology, Dongsan Medical Center, Keimyung University School of Medicine.
엑시머레이저 굴절교정각막절제술과 엑시머레이저 각막절삭 가공성형술 후 각막내피세포의 변화
김기산(Ki San Kim),백승호(Seung Ho Baek)
Abstract
To evaluate endothelial cell changes after excimer laser surgery, we per-formed noncontact specular microscopy (Konan,CA.SP.8000.Japan) preoperatively, one week and 3, 6, 9 and 12 months after surgery to observe the central corneal endothelium of the eyes which underwent PRK (165 eyes) and LASIK (70 eyes). Corneal endothelial density (CD), coefficient of variation of the cell area (CV), and percentage of hexagonal cells (hexagonality, 6A) were obtained according to the corneal endothelial cell analysis program. Considering the cases which showed increased CD, decreased CV, or increased 6A as it had no changes, rate of each parameter were calculated. The mean CD was 2,838/mm2preoperatively, and 2,831/mm2at 12 months after PRK, with decreasing rate of 2.66%. Although preoperative CD was higher than that of 12 months after LASIK (preop: 2,682/mm2, 12 month: 2,735/mm2), its decreasing rate was 4.65%. In PRK group, CV seemed to have decreased at postoperative 12 months(preop: 36.97, postop 12 months: 33.76) but its increasing rate was 3.96%.In LASIK group, CV was 36.91 preoperatively, and 36.66 at postoperative 12 months but its increasing rate was 11.47%. In PRK group, the mean preoperative and postoperative 12 months 6A were 57.23 and 55.92%respectively. Its decreasing rate was 8.01%.In LASIK group, it was 57.19%preoperatively and 55.44% 12 months after LASIK. Its decreasing rate was 8.30%. The result showed that excimer laser treatment might have caused minor endothelial damage which would be clinically insignificant.
Key Words: Corneal endothelial cell density;Hexagonality;LASIK;Polymegathism;PRK


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