Normal values of Focal Electroretinograms, and the Clinical Applications.

Kim, Jung Hwan; Ohn, Young Hoon; Shin, Han Ho

Original Article

Journal of the Korean Ophthalmological Society 1997;38(6):976-984.
Published online June 1, 1997.

Normal values of Focal Electroretinograms, and the Clinical Applications.

Jung Hwan Kim, Young Hoon Ohn, Han Ho Shin

Department of Ophthalmology, School of Medicine, Soonchunhyang University, Seoul, Korea.

국소망막전위도의 정상치 및 임상적 응용

김정환(Jung Hwan Kim),온영훈(Young Hoon Ohn),신환호(Han Ho Shin)

Abstract

Focal cone electroretinograms were performed with 5-degree white flickering stimuli on 100 normal eyes and 50 eyes with known macular diseases. Responses were obtained under direct visualization of the fundus with hand-held stimulator-ophthalmoscope (FSC-500) produced by LKC Technologies. Mean foveal cone amplitude for 100 normal eyes was 449.6 nV and mean implicit time was 34.8 msec, and ninty five percent of normal eyes had amplitudes greater than 320 nV, and implicit time less than 48.5 msec. There was a statistically significant inverse correlation between amplitude from fovea and age (r=-0.93, p< 0.05). In eyes with known maculopathy, mean foveal cone amplitude was well correlated with visual acuity. Over ninty percent (29/32) of eyes with visual acuity of 0.5 or poorer showed significant reduction in amplitude, even after correcting aging effect. We suggest that the focal electroretinogram is a sensitive and useful test for detecting macular abnormalities.

Key Words: Aging;focal electroretinogram;clinical application