Journal of the Korean Ophthalmological Society 1997;38(7):1221-1228.
Published online July 1, 1997.
A Comparison of the Responses to Diode and Argon Laser Irradiation of the Iris in Rabbits.
Yong Yeon Kim, Tae Soo Lee
Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
다이오드 및 아르곤 레이저 홍채조사후 반응에 관한 비교연구
김용연(Yong Yeon Kim),이태수(Tae Soo Lee)
Abstract
We compared the effects of diode laser (DL) irradiation of the iris with those of argon laser (AL). Histopathologic examination of laser-induced lesion, measurements of aqueous flare and prostaglandin (PG) E2 were performed. DL was applied in one eye of each animal and the fellow eye received ALwith the same parameters in 49 pigmented rabbits. At 1 hour after irradiation, the mean flare count was higher in the DL-treated eyes than in AL-treated eyes(p<0.05). However, the concentrations of PG E2 and intraocular pressures were similar between the DL- and AL-treated eyes(p>0.05). On histopathologic examinations, iris defect by DL was wider and shallower than that by AL. The extent of coagulation of the iris tissue was more extensive in the DL-irradiated iris. Our results suggest that the DL irradiation may be more harmful to the blood-aqueous barrier and iris tissue than AL. Further development of the laser equipment or the treatment regimen for diode laser iridotomy may be necessary.
Key Words: Argon laser;Diode laser;Flare;Lntraocular pressure;Iris;Laser iridectomy;Prostaglandin


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