| Surgical Outcome of Intraoperative Episcleral Application of 5-Fluorouracil in Primary Trabeculectomy. |
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Jong Gyoo Yang, Changwon Kee |
1Department of Ophthalmology, Colleg of Medicine, Seoul National University, Seoul, Korea.
2Department of Ophthalmology, Samsung Medical Center, College of Medicine, Sung Kyun Kwan University. |
| 수술중 5-FU를 상공막에 적용한 1차 섬유주절제술의 임상 분석 |
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양종규(Jong Gyoo Yang),기창원(Chang Won Kee) |
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| Abstract |
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We analyzed the outcome of primary trabeculectomy performed with intraoperative 5-fluorouracil(5-FU) sponge application on episclera and under lamella scleral flap in seventeen uncomplicated glaucoma eyes. The mean preoperative intraocular pressure(IOP) was 36.8+/-11.0mmHg. The mean postoperative IOP was 14.2+/-3.5mmHg after mean follow-up of 11.4 months. Two eyes required additional anti-glaucoma medications. Compliations included chronic hypotony(1 eye), shallow anterior chamber(2 eyes), and hyphema (1 eye). No eye showed corneal problems, hypotonic maculopathy, and bleb leakage. This study suggests that a single intraoperative use of 5-FU in primary trabeculectomy is an effective way of improving IOP control and of decreasing complications in eyes with uncomplicated glaucoma. |
| Key Words:
5-fluorouracil;trabeculectomy;uncomplicated glaucoma |
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