Intravitreal Tissue Plasminogen Activator and Gas Injection in Submacular Hemorrhage.

Kim, Il Kyung; Hahn, Duk Kee

Original Article

Journal of the Korean Ophthalmological Society 1997;38(10):1870-1874.
Published online October 1, 1997.

Intravitreal Tissue Plasminogen Activator and Gas Injection in Submacular Hemorrhage.

Il Kyung Kim, Duk Kee Hahn

Department of Ophthalmology, College of Medicine, Yeungnam University, Taegu, Korea.

유리체강내 Tissue Plasminogen Activator 및 가스주입에 의한 황반부 망막하출혈의 치료 1례

김일경(Il Kyung Kim),한덕기(Duk Kee Hahn)

Abstract

Tissue plasminogen activator(tPA) has been used as useful adjunct in the submacular hemorrhage due to age-related macular degeneration, which was injected and able to dissolve clotted blood. It was also known that intravitreal injection of tPA was effective as much as subretinal injection for lysis of blood. Recently, the rationale was introduced that residual dissolved subretinal blood with tPA was displaced from fovea away by intravitreal injection of an expanding gas. We have experienced the improvement of vision in an 83-year old woman with submacular hemorrhage, treated with intravitreal tPA and gas injection.

Key Words: gas;submacular hemorrhage;tissue plasminogen activator