Quantitative Measurement of Choroidal Blood Flow in Rabbits.

Kim, Sang Min

Original Article

Journal of the Korean Ophthalmological Society 1966;7(1):7-13.

Quantitative Measurement of Choroidal Blood Flow in Rabbits.

¹Department of Ophthalmology, Catholic Medical College, SeauI, Korea.
²Department of Ophthalmology, School of Medicine, Seoul Nalional Univesity, Seoul, Korea.

맥락막 (脈絡膜) 혈류측정에 (血流測定) 관한 (關) 연구 (硏究)

윤원식(Won Sik Yoon),김상민(Sang Min Kim)

Abstract

An apparatus was designed, based on the principle of Grayson's internal calorimetry, for the determination of the choroidal blood flow with thermistor as a sensing element. Experiments with water; 10%, 20%, 30% and 50% gelatin solution; living and dead rabbit eye and enucleated human eye showed that there was a linear relationship between the thermal conductivities and the currents required to raise the heating thermistor by 1 degree. Thus it was found that the Carslaw's law could be applied in these experiments In rabbit's eyes, thermistors were introduced into the suprachoroidal space after separating the sclera from the underlying choroid. At the same time, one of the vortex veins was cut right after the vein emerge from the sclera, and the amount of blood was absorbed and weighed. The results showed that when the blood flow was in the lower range, the thermal conductivity increased abruptly. When the blood flow increased, the increase in the thermal conductivity was at a more slower rate. In the physiological range of blood flow, however, there was a linear relationship between the blood flow and the changes in the thermal conductivity.