Journal of the Korean Ophthalmological Society 1998;39(9):1959-1970.
Published online September 1, 1998.
The Quantitative Analysis of Tear Total Protein and Lysozyme in Normal and Diabetes.
Beak Ran Song
Department of Ophthalmology, Inha Hospital, Inha University, Inchon, Korea.
정상인과 당뇨병 환자의 누액 총단백질과 리소자임의 정량분석
송백란(Baek Ran Song)
Abstract
The various ocular diseases affects the components of ocular tear film. And the tear protein analysis may be of considerable diagnostic value s the ocular pathologic marker in the complex systemic diseases such as diabetes. To compare the amounts of the total tear protein and the tear lysozyme concentration in normal persons with those of diabetic patients the tear protein with 141 eyes in 141 normal persons and 86 diabetic patients were analysed. Conclusively, the tear lysozyme concertration is decreased in diabetes. The risk factors are older age, longer duration of diabetes, more severe diabetic retinopathy, and the presence of systemic diabetic complications such as diabetic nophropathy. The tear lysozyme concentration is an good indicator in the diabetic dysfunction of the main and accessory lacrimal gland. And it is suggested that the Qualitative change of tear composition in diabetes is associated with the main and accessory lacrimal gland dysfunction.
Key Words: Lysozyme;Tear Protein;Tear Film;Diabetes


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