A Clinicopathologic Study of 46 Cases of Eyelid Malignancy.

Lee, Tai Won; Yang, Sung Wook; Kim, Byeong Hee; Song, Joan Seok

Original Article

Journal of the Korean Ophthalmological Society 1995;36(12):2087-2094.
Published online December 1, 1995.

A Clinicopathologic Study of 46 Cases of Eyelid Malignancy.

Tai Won Lee, Sung Wook Yang, Byeong Hee Kim, Joan Seok Song

Department of Ophthalmology, KCCH, Seoul, Korea.

악성안검종양 46 예에 대한 임상연구 및 병리 조직학적 고찰

이태원(Tai Won Lee),양성욱(Sung Wook Yang),김병희(Byeong Hee Kim),송준석(Joon Seok Song)

Abstract

We studied retrospectively 46 patients of primary malignant eyelid tumors who were histologically diagnosed in Korea Cancer Center Hospital from May, 1987 to December, 1994 and followed for 6 months or longer. 46 patients consist of, 22 cases of basal cell carcinoma(47.8%), 10 cases of squamous cell carcinoma(21.7%), 9 cases of sebaceous gland carcinoma(19.6%), and 5 cases of malignant melanoma(10.9%). Our modalities of treatment for eyelid malignancy included excision under frozen-section control, radiotherapy and cryotherapy. In case of regional lymph node metastasis we performed radiation treatment with or without excision of primary tumor and regional lymph node dissection. A case with distant metastasis underwent radiotherapy combined with chemotherapy. Following initial treatment, 4 cases showed recurrence and 3 cases developed regional or distant metastasis. In this study, we emphasize that suspected eyelid malignancy should be histologically diagnosed with biopsy and treated adequately at an early stage to reduce recurrence or metastasis.

Key Words: Basal cell carcinoma;Eyelid;Malignant melanoma;Malignancy;Sebaceous gland carcinoma;Squamous cell carcinoma