The Immunologic Reactions of Non-swelling Corneas.

Lee, Jin Hak

Original Article

Journal of the Korean Ophthalmological Society 1975;16(1):24-31.
Published online January 1, 1975.

The Immunologic Reactions of Non-swelling Corneas.

Jin Hak Lee

Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.

비종창 각막의 면역반응

이진학 ( Jin Hak Lee )

Abstract

The treatment of corneal stroma by bifunctional aldehydes and bibasic aminoacids in order to make non-swelling corneas was performed with the corneas of rabbits and cocks. The non-swelling corneas were transplanted into rabbits, intra-lamellarly and lamellarly. Their clinical and histological examinations were given, below. 1) Intralamellar grafts. The group used the non-swelling corneas: No edema, opacity and vascularizations were observed. Mild inflammatory reactions were observed in the histological examinations. Control group: Typical immunologic reactions were observed, such as severe edema, opacities, and vascularization and heavy infiltration of eosinophils and small round cells. 2) Lamellar grafts. The group used the non-swelling corneas: No edema and vascularization were observed except mild opacity in the heterograft. Mild inflammatory reactions were observed in the histologic examination of the heterograft. Control group: No immunologic reactions were observed in homograft, while severe opacities and edema were observed in heterograft. Severe vascular engorgement and heavy infiltration of eosinophils and small round cells were observed in the histologic examination of heterograft.