The Necessity of Topical Corticosteroid After Excimer Laser Photorefractive Keratectomy.

Lee, Jun Gyo; Kim, Woo Jung; Lee, Jin Hak

Original Article

Journal of the Korean Ophthalmological Society 1996;37(5):913-920.
Published online May 1, 1996.

The Necessity of Topical Corticosteroid After Excimer Laser Photorefractive Keratectomy.

¹Department of ophthalmology, Seoul National University Hospital, Korea.
²Department of ophthalmology, Samsung Medical Center, Seoul, Korea.

굴절교정레이저 각막절제술 후 스테로이드 점안의 필요성

이준교(Jun Gyo Lee),김우중(Woo Jung Kim),이진학(Jin Hak Lee)

Abstract

The effect of topical steroid application on clinical results of 215 eyes(126 patients) performed with excimer laser photorefractive keratectomy (PRK) from July 1993 to July 1994 was evaluated, postopertively. The range of myopia was between -2.5 and -11.5 diopter and followed for 9 months after PRK with Summit Omnimed(TM). Topical corticosteroid or non-steroidal antiinflammatory drug (NSAID) was not applied for one month after operation in all cases. After one month, in cases of 115 eyes showing myopic regression of more than -1 diopter or stromal haziness of more than grade 1(delayed steroid group; DSG), 0.1% fluorometholone was applied 4 times daily for 4 weeks, then tapered according to the planned schedule. 46.5% (100 eyes, non-steroid group;NSG) did not show the myopic regression nor stromal haziness without treatment of fluorometholone throughout the follow-up period. Uncorrected visual acuity, spherical equivalent and corneal haziness were evaluated 1, 2, 4, 8, 12, 24, 36 week after operation. 73%(73 eyes) of NSG and 27%(30 eyes) of DSG showed a myopia less than 6.0 diopters preoperatively. The proportion of male was 36% in NSG and 50.4% in DSG. 88.1% of male high myopia(>6.0 diopters) needed 0.1% fluorometholone, while 17.6% of female moderate and mild myopia(

Key Words: Corneal haziness;Excimer laser photorefractive keratectomy;Myopic regression;Topical steroid