Journal of the Korean Ophthalmological Society 1996;37(6):1005-1011.
Published online June 1, 1996.
Clinical Characteristics of the Retinoblastoma Diagnosed before One Year Old.
Jong Gyoo Yang, Young Suk Yu
Department of OphthaIm6logy, College of Medicaine, Seoul National University, Seoul, Korea.
1세전에 진단된 망막모세포종의 임상 특징
양종규(Jong Gyoo Yang),유영석(Young Suk Yu)
Abstract
To evaluate the clinical characteristics of retinoblastoma diagnosed before one year old. 19 children with retinoblastoma were observed with clinical records, retrospectively. Thirteen patients had unilateral retinoblastoma. and 6 patients had bilateral retinoblastoma. The mean age at diagnosis was 6.5 months. Patients of bilateral retinoblastoma were younger than those of unilateral retinoblastoma. Sixteen patients had leukocoria. No patients had a known family history. Under Reese-Ellsworth retinoblastoma classification system, 13 eyes(52%) were initially seen with group 4,5 tumors, 16 eyes(64%) were treated with group 4,5 tumors. Eight eyes(32%) had extraocular local metastasis. No eye had distant metastasis. Seventeen eyes(68%) were treated with enucleation or orbital exentration. Four eyes required additional treatment because of 2 eyes for recurrence and 2 eyes for new tumor. For a mean of 31.6 months, 2 children died, but there was no evidence of distant metastasis. These results show the retinoblastoma diagnosed before one year old tend to have bilateral tumor and to be more advanced, therefore the vigorous efforts for diagnosis and treatment should be done.
Key Words: Enucleation;Leukocoria;Retinoblastoma


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