| The Effect of Corticosteoid Treatment on Myopic Regression after Photorefractive Keratectomy. |
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Kyung Ho Woo, Ki San Kim |
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Department of Ophthalmology, College of Medicine, Keimyung, Taegu, Korea. |
| 엑시머 레이저 근시 교정술 후 근시로의 역행시 스테로이드의 치료 효과 |
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김기산(Ki San Kim),우경호(Kyung Ho Woo) |
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| Abstract |
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With the aim of reversing myopic regression after PRK, the effect of highdose topical corticosteroid in modulating changes in refraction and corneal transparency were assessed prospectively. Seventy-two eyes of 62 patients (mean preoperative SE -6.14D; -2.30 D to -11.50D), demonstrating myopic regression ranging between -0.75D to -5.33D (mean: -1.69D), were treated with 0.1% dexamethasone eye solution five times a day for averaging 2.8 weeks. The age of patient, amount of attempted correction and K-reading did not influenced statistically significantly on myopic regression. Uncorrected visual acuity, mean refraction before reintroducing corticosteroids (mean: 0.58, -1.69D) improved after corticosteroid treatment (mean: 0.85, -0.42D)(p<0.01). Corneal haze changed statistically significant from 0.80 +/- 0.61 to 0.53 +/- 0.40 after steroid treatment(p<0.01). Topical corticosteroid therapy can modulate refractive changes after PRK, appearing to improve myopic regression. However, a long term follow up will be necessary to determine the final refractive outcome of these eyes. |
| Key Words:
Excimer laser;Myopic regression;Photorefractive keratectomy;Corticosteroid |
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