| Histopathological Study of Corneal Wound Healing after Holmium : YAG laser Thermokeratoplasty in Rabbit. |
|
J Y Kim, Y J Lee, Y S Choi, K H Lim, J H Lee |
1Department of Ophthalmology, Seoul National University College of Medicine.
2Department of Ophthalmology, College of Medicine, Chungbuk National University. |
| Holmium: TAG 레이저 열각막성형술 후 토끼 각막 창상 치유의 조직병리학적 연구 |
|
김지영(Kim J.Y),이용재(Lee Y.J),최용석(Choi Y.S),임기환(Lim K.H),이진학(Lee J.H) |
|
|
|
|
| Abstract |
|
The animal study was conducted to investigate the histopathologic effect of holmium: YAG laser thermokeratoplasty on the rabbit cornea. Ten eyes of five shite rabbits received holmium: YAG laser thermokeratoplasty, and hematoxylin & eosin staining and immunohistochemical staining for type II, IV, VI collagen were performed at 1,2,4,12, and 20 weeks following irradiation. Corneal endothelium was not changed. The hyperplasia of epithelium and disorganized stromal architecture appeared in early postoperative period had been normalized until 20 weeks. There was no difference in type III collagen staining between untreated and irradiated tissue at any postoperative period. Type IV collagen at epithelial basement membrane has been present intnsely until 20 weeks, and increased type VI collagen in stroma disappeared at 20 weeks after holmium: YAG laser thermokeratoplasty, and some problems may remain in adgesion between the epithelium and the stroma because of the change of type IV collagen. |
| Key Words:
Histopathologic effect;Holmium: YAG laser thermokeratoplasty |
|
PDF Links
Download Citation
