The Clinicopathologic Characteristics of Lymphoid Tumor of The Orbit and Ocular Adnexa.

Kee, Tae Soo; Rhee, Kyu Chul; Hong, Jong Wook

Original Article

Journal of the Korean Ophthalmological Society 1997;38(4):517-523.
Published online April 1, 1997.

The Clinicopathologic Characteristics of Lymphoid Tumor of The Orbit and Ocular Adnexa.

Tae Soo Kee, Kyu Chul Rhee, Jong Wook Hong

Department of Ophthlmology, School of Medicine, Korea University.

안와 및 안와 부속기 임파성 종양의 임상 및 조직병리학적 특성

이태수(Tae Soo Lee),이규철(Kyu Chul Rhee),홍종욱(Jong Wook Hong)

Abstract

The authors reivewed retrospectively the medical records and pathologic slides of 18 patients with the orbital lymphoid tumors that had been confirmed pathologically. Pathologic diagnoses were as follows : 14 cases of pseudolymphoma (benign reactive hyperplasia), 2 cases of atypical lymphoid hyperplasia and 2 cases of malignant lymphoma. Of the 18 patients, 7 cases were male and 11 were female. The average age at first visit was 53 years. Palpable or visible mass was the most frequent presenting symptom. There were no significant differences in clinical characterstics and radiologic findings between benign and malignant tumors. Determination of clonality of tumors by immunohistochemical study was useful method to differentate pseudolymphoma and atypical lymphoid hyperplasia from malignant lymphoma. An accompanying systemic disease was not found in all cases. All patients were received local orbital irradiation. Regression or disappearance of masses was noted in all cases. No patient have experienced recurrence or development of systemic disease during the mean follow-up of 30 month.

Key Words: Pseudolymphoma (Benign reactive hyperplasia);Atypical lymphoma Phoid hyperplasia;Malignant lymphoma;Immunohistochemical study;Orbital irradiation