The Effect of Cyclosporin Therapy on Endogenous Uveitis.

Lee, Eui Tae; Kim, Min Ho; Chung, Sang Moon

Original Article

Journal of the Korean Ophthalmological Society 1997;38(4):601-607.
Published online April 1, 1997.

The Effect of Cyclosporin Therapy on Endogenous Uveitis.

Eui Tae Lee, Min Ho Kim, Sang Moon Chung

Department of Ophtahlmology, Catholic University Medical College, Seoul, Korea.

내인성 포도막염에서의 싸이클로스포린의 치료효과

이의태(Eui Tae Lee),김민호(Min Ho Kim)

Abstract

Endogenous uveitis is characterized by frequent remissions and exacerbations which lead to visual loss, and treated with immunosuppresive agents. We evaluated the therapeutic effect and complicantions of 15 patients (25 eyes) with endogenous uveitis who were treated with cyclosporin (Implanta). The inflammatory activities of anterior chamber and vitreous were reduced significantly after 1, 3, and 8 month follow-up of cyclosporin therapy, and the visual acuity was improved or sustaind in 52% of all patients. If cyclosporin therapy is intolerable, combining the cyclosporin with low dose of a steroid should be considered.

Key Words: Endogenous uveitis;Cyclosporin;Steroid