Effect of Ganciclovir on cytomegalovirus Retinitis of a Renal Transplant Patient without Maintenance Therapy.

Cho, Chul Woong; Park, Yeong Min; Seo, Man Seong

Original Article

Journal of the Korean Ophthalmological Society 1997;38(4):637-642.
Published online April 1, 1997.

Effect of Ganciclovir on cytomegalovirus Retinitis of a Renal Transplant Patient without Maintenance Therapy.

Chul Woong Cho, Yeong Min Park, Man Seong Seo

¹Department of Ophthalmology, College of Medicine, Korea University, Seoul, Korea.
²Department of Ophthalmology, Chonnam University Hospitial.

신이식후 발생한 거대세포바이러스망막염에 있어 Ganciclovir 유도요법만의 효과

조철웅(Chul Woong Cho),박영민(Yeong Min Park),서만성(Man Seong Seo)

Abstract

Cytomegalovirus retinitis (CMV), an opportunistic infection of a immunocompromised patient, is a necrotizing retinitis occurred in AIDS or the patient using immunosuppressants. A 31-years-old male taken immunosuppressants after renal transplantation, had white granular foci and perivascular sheathings in the uper temporal retina of both eyes. Serologic test demonstrated positive response to bith IgG and IgM antibody against CMV. Argon laser photocoagulation was done and ganciclovir was intravenously treated 300 mg every 12 hours for three weeks without maintenance therapy. Nine months after treatment, there was no recurrence of retinitis. This result suggests CMV retinitis of renal transplanted patient may not need the maintenance therapy of ganciclovir.

Key Words: Cytomegalovirus;Ganciclovir;Maintenance therapy;Renal transplantation