Postmortem Change of Adhesive Forces Between the Retina and the Retinal Pigment Epithelium.

Yun, Young Soo; Kwon, Oh Woong

Original Article

Journal of the Korean Ophthalmological Society 1993;34(2):111-116.
Published online February 1, 1993.

Postmortem Change of Adhesive Forces Between the Retina and the Retinal Pigment Epithelium.

Young Soo Yun, Oh Woong Kwon

망막과 망막색소상피간 결합력의 사후 변화

윤영수(Young Soo Yun),권오웅(Oh Woong Kwon)

Abstract

Adhesive forces between the retina and the retinal pigment epithelium, which is mainta ined by active mechanisms unique for living animals, deteriorates rapidly after death and leads to spontaneous retinal detachment. Change of retinal adhesiveness in rabbits after death was investigated using a new method. Retinal detachment was induced by applying various levels of aspiration power from 0 to 1OO mmHg to the vitreous cavity using a vitrectomy instrument immediately after the rabbit was killed without enucleation. And the time required for creating the retinal detachment was measured. Retinal adhesiveness deteriorated and spontaneous retinal detachment occurred 28 minutes and 35 seconds after death confirming the active adhesion between the retina and the retinal pigment epithelium before death Increase of aspiration power led to shortening of time required for creating retinal detachment. From aspiration powers of 0 to 100 mmHg, the common logarithm of time required for retinal detachment was inversely proportional to the aspiration power [IogY = 1.45215 - 0.01113X, (R2=0.99041), X: aspiration power (mmHg), Y: time required for creating retinal detachment (minutes)]. Thus, presumed time of retinal detachment could be estimated between the aspiration powers of 0 to 100 mmHg.

Key Words: Adhesive foreces;Retinal detachment;Aspiration power;Common logarithm