Journal of the Korean Ophthalmological Society 1993;34(9):881-888.
Published online September 1, 1993.
Effect of Plasma Coagulation Factor XIII Deficiency on the Healing Following Trabeculectomy in Rabbits.
Jin Kap Kim, Hyeong Ki Han, Suk Dong Kim
Department of Ophthalmology, Catholic University, Medical College, Holy Family Hospital, Pucheon, Korea.
가토에서 혈장응고인자 8 결핍에 의한 섬유주절제수술창의 조직학적 변화
김진갑(Jin Kap Kim),한형기(Hyeong Ki Han),김석동(Suk Dong Kim)
Abstract
Conjunctival fibroblastic proliferation with contracting scar formation has been implicated as a possible cause of glaucoma filtering surgery failure. The inhibitory effect of plasma coagulation factor XIII deficiency on the healing following trabeculectomy of the eyes in rabbits was studied. The plasma coagulation factor XIII deficiency was induced by two successive intravenous injections of anti-rabbit plasma coagulation factor XIII-goat immunoglobulin. Grossly, artificially prepared filtering bleb was well preserved on plasma coagulation factor XIII ddicient groups compared with control groups. Histologically. wound healing following trabeculectomy was delayed and the size of the scar was reduced on plasma coagulation factor XIII deficient groups compared with control groups. The above findings suggest that plasma coagulation factor XIII deficiency inhibit the healing precess following traheculectomy.
Key Words: Filtering bleb;Plasma coagulation factor XIII;Trabeculectomy;Wound healing


ABOUT
BROWSE ARTICLES
EDITORIAL POLICY
FOR CONTRIBUTORS
Editorial Office
SKY 1004 Building #701
50-1 Jungnim-ro, Jung-gu, Seoul 04508, Korea
Tel: +82-2-583-6520    Fax: +82-2-583-6521    E-mail: kos08@ophthalmology.org                

Copyright © 2024 by Korean Ophthalmological Society.

Developed in M2PI

Close layer
prev next