A Case of Chronic Progressive External Ophthalmoplegia.

Shin, Won Kyu; Choi, Byung Su; Shin, Hanho

Case Report

Journal of the Korean Ophthalmological Society 1995;36(1):120-124.
Published online January 1, 1995.

A Case of Chronic Progressive External Ophthalmoplegia.

Won Kyu Shin, Byung Su Choi, Hanho Shin

Department of Ophthalmology, College of Medicine, Soonchunhyang University, Hospital, Seoul, Korea.

만성진행 외안근마비증 1 예

신원규(Won Kyu Shin),최병수(Byung Su Choi),신환호(Hwan Ho Shin)

Abstract

Chronic progressive external ophthalmoplegia(CPEO) is rare syndrome, which is characterized by slowly progressive blepharoptosis, paralysis of extraocular muscle and has involvement of other organs, particularly the retina, heart, endocrine gland, and bony skeleton. Histological examination of muscle showes characteristic ragged red fibers. Electron microscopy reveals a number of abnormal mitochondria which contain paracrystalline inclusion bodies. We experienced a 50-year-old female with CPEO, that was pathologically proven by electron microscopy and bilateral levator levator advancements were given for ptosis.

Key Words: CPEO;Abnormal mitochondria;ptosis;ragged red fiber