Journal of the Korean Ophthalmological Society 1991;32(6):434-440.
Published online June 1, 1991.
Two Cases of Pellucid Marginal Corneal Degeneration.
Seo Hark Lee, Tae Won Hahn, Man Soo Kim, Jae Ho Kim
Department of Ophthalmology, Kangnam St. Mary's Hospital, Catholic University Medical College, Seoul, Korea.
Pellucid Marginal Corneal Degeneration 2 예
김만수(Man Soo Kim),김재호(Jae Ho Kim),이서학(Seo Hark Lee),한태원(Tae Won Hahn)
Abstract
Pellucid marginal degeneration is an uncommon, idiopathic, non-inflammatory, peripheral thinning disorder affecting the inferior cornea bilaterally. Protrusion of the cornea occurs above a band of thinning which is located 1 to 2mm from the limbus and measures 1 to 2mm in width. The disease is diagnosed usually between 20 and 50 years of age and its etiology remains obscure. We experienced two cases of pellucid marginal degeneration who had a histories of progressIve visual disturbance due to high irregular astigmatism. A 32 year old female(case.1) had the characteristic feature of pellucid marginal corneal degeneration with marked endothelial cell loss(OD. 624 +/- 32 cells/mm2, OS. 596 +/- 52 cells/mm2) in polymorphism. A 30 year old male(Case. 2) showed pellucid marginal corneal degeneration associated with rheumatoid athritis, but corneal endothelial cells appeared within normal ranges(OD. 2764 +/- 26, OS. 2812 +/- 34) with slight polymorphism. The Vision in these two cases improved to 20/20 with hard contact lens(Case. 1) and glasses(Case.2)
Key Words: Corneal thinning disorder;Pellucid marginal degeneration;Astigmatism;Corneal endothelial cells


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