Journal of the Korean Ophthalmological Society 1992;33(1):68-73.
Published online January 1, 1992.
Effect of Apraclonidine Hydrochloride on the Acute Intraocular Pressure Rise after Argon laser Iridotomy.
Chul Hong, Ki Yung Song, Woo Hyung Park, Young Ho Sohn
1Dr. Hong's Eye Clinic, Seoul, Korea.
2Department of Ophthalmology, Red-cross Hospital, Seoul, Korea.
3Dr. Park's Eye Clinic, Seoul, Korea.
4Dr. Sohn's Eye Clinic, Seoul, Korea.
알곤레이저 홍채절개술후 안압상승에 대한 Apraclonidine Hydrochloride 의 효과
홍철(Chul Hong),송기영(Ki Yung Song),박우형(Woo Hyung Park),손영호(Young Ho Sohn)
Abstract
To determine the effect of apraclonidine hydrochloride on the acute intraocular pressure (IOP) rise after argon laser iridotomy (ALl), a double-masked comparative study was carried out. Twenty-nine eyes (20 patients) with angle-closure glaucoma underwent ALL Eighteen eyes were treated with apraclonidine and the remainder received placebo 1 hour before and immediately after ALl. The mean IOP increase in the apraclonidine group was lower than that in placebo group at each postlaser intervals (p<0.01). Although average value of maximal increases of IOP after ALl in apraclonidine group was 4 mmHg, that in placebo group was 16mmHg. 27.3% (3 out of 11 eyes) in placebo group experienced IOP rise greater than or equal to 10 mmHg, however, that kind of IOP rise was not found in apraclonidine group (0 out of 18 eyes) (p
Key Words: Angle-closure glaucoma;Apraclonidine;Argon laser iridotomy (ALl);Intraocular pressure (lOP)


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