| Immunohistochemical Study of Proliferative Vitreoretinal Membranes. |
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Sang In Kwak, Se Oh Oh, Hum Chung, Jaeheung Lee |
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Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea. |
| 초자체 망막 증식성막의 구성세포에 관한 면역조직학적 연구 |
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곽상인(Sang In Kwak),오세오(Se Oh Oh),정흠(Hum Chung),이재흥(Jae Heung Lee) |
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| Abstract |
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To identify the cellular components of proliferative vitreoretinal membranes. 11 proliferative vitreoretinal membranes which were surgically obtained from 7 eyes with proliferative vitreo retinopathy (PVR) and 4 eyes with proliferative diabetic retinopathy (PDR) were stained with monoclonal antibodies against cytokeratin, glial fibrillary acidic protein(GFAP), or vimentin using immunoperoxidase technique (ABC method). In PVR membranes, mean cell positivities for cytokeratin, GFAP and vimentin were 48%, 1% and 92%, respectively and in PDR membranes, 0%, 5% and 93%, respectively. The above results suggest that retinal pigment epithelial celIs and fibroblasts are major cellular components of PVR membranes, and mesenchymal cells are major cellular components and glial cells minor cellular components of PDR membranes. |
| Key Words:
Cellular component;Immunohistochemical study;Proliferative diabetic retinopathy;Proliferative vitreoretinopathy;Proliferative vitreoretinal membrane |
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