The Standardization of Electroretinogram C-wave in Pigmented Rabbits.

Jo, Young Soo; Kim, Si Yeol

Original Article

Journal of the Korean Ophthalmological Society 1987;28(2):363-369.
Published online February 1, 1987.

The Standardization of Electroretinogram C-wave in Pigmented Rabbits.

Young Soo Jo, Si Yeol Kim

Department of Ophthalmology, School of Medicine, Kyungpook National University, Taegu, Korea.

유색가토에서의 ERG C 파의 표준화

조영주(Young Soo Jo),김시열(Si Yeol Kim)

Abstract

The electroretinogram c-wave is known as a good electrophysiologic test of retinal pigment epithelial function, but its large inter and intra individual variation prevented clinical and experimental application. We recorded a stable c-wave in pigmented rabbits and the following result was obtained. Under dark adaptation state the c-wave amplitude reached equilibrium after 60 minutes, but its interindividal variation was large. The similar c-wave amplitude of right and left eye indicates that contralateral eye can be used as a control during local administration of drugs. The interindividual variation of c-wave amplitude under dim light is much smaller than under dark adaptation. This may be a good indicator in pharmacologic experiment of systemically administered drugs.