Treatment of Blepharospasm with Botulinum A Toxin.

Kim, Yoon Duck; Levine, Mark R

Original Article

Journal of the Korean Ophthalmological Society 1987;28(3):523-529.
Published online March 1, 1987.

Treatment of Blepharospasm with Botulinum A Toxin.

¹The Mt. Sinai Medical Center Cleveland, Ohio, USA.
²Division of Ophthalmology Eulji Hospital, Seoul, Korea.
³Division of Ophthalmology, The Mt. Sinai Medical Center, Ohio, USA.
⁴Case Western Reserve University, USA.
⁵Oculoplastics Clinic University, Hospitals of Cleveland, Cleveland, Ohio, USA.

Botulinum A toxin 을 사용한 안검경련의 치료

김윤덕(Yoon Duck Kim) , (Mark R. Levine)

Abstract

Thirty-nine patients with blepharospasm were treated with botulinum A toxin. Twenty-six patients had essential blepharospasm, and thirteen had hemifacial spasm. A total of 113 injections were given, and average follow-up was 14.6 months. The mean preinjection spasm intensity was 2.9+, and the mean post-injection spasm intensity was 0.7+. The mean interval between injections was 4.4 months. The treatment was effective, although transient, in all patients with essential blepharospasm and hemifacial spasm. The toxin had a prolonged effect on the patients who had previously undergone muscle stripping proced ure. The side effects were mild, transient, and local.