The Role of Microfibril in Pathogenesis of Exfolion Syndrome.

Roh, Young Bae; Bak, Byung Guk

Original Article

Journal of the Korean Ophthalmological Society 1987;28(6):1289-1296.
Published online June 1, 1987.

The Role of Microfibril in Pathogenesis of Exfolion Syndrome.

Young Bae Roh, Byung Guk Bak

Department of Ophthalmology, College of Medicine, Pusan National University, Pusan, Korea.

탈락성 증후군 ( Exfoliation Syndrome ) 의 병인에서 microfibril 의 역할

노영배(Young Bae Roh),박병국(Byung Guk Bak)

Abstract

We electron-microscopically studied 15 specimens of upper limbal conjunctiva obtained from 14 patients with exfoliation syndrome and clinical evidence of glaucoma. Of 15 specimens, four(three patients) contained exfoliation materials in the stroma of the stroma of the conjunctiva. These exfoliation materials of immature, intermediate, and mature forms were composed of abnormal microfibrils lying adjacent to the fibroblasts and located in close proximity to the elastic and collagen fibers. These observations suggest a sequence of events by which microfibrils develop into exfoliation materials.