Protease Activities in Various Kinds of Enzymatic Cleaners for Contact Lenses.

Kim, Jae Ho; Tanouchi, Hiroshi

Original Article

Journal of the Korean Ophthalmological Society 1988;29(1):69-75.
Published online January 1, 1988.

Protease Activities in Various Kinds of Enzymatic Cleaners for Contact Lenses.

¹Department of Ophthalmology, Kangnam St. Mary's Hospital, Catholic University, Medical College, Seoul, Korea.
²Contact Lab., Ophtecs Corp. Tokyo 103, Japan.

콘택트렌즈의 여러가지 효소세정제에 대한 단백분해능의 비교

전내박(Hiroshi Tanouchi),김재호(Jae Ho Kim)

Abstract

UV-absorption method was able to determine protease activities in various kinds of enzymatic cleaners. Bioclen G and O2 had high protease activities at room temperature and were effective for artificial protein deposits; Bioclen G is safe for the eyes because enzyme was inactivated at 70 degrees C. Both products were better enzymatic cleaners for both hard and soft contact lenses. Hydrocare-F was effctive for removing artificial protein deposits. For the sake of safety against the eyes, there was a problem in that this product had too high proteasea activity at 90 degrees C. Protease activities were generally lower or showed great variations at 10 ~ 30 degrees C for other products. These had lower cleaning effect for artificial protein deposits on rigid gas permeable contact lenses.