Electroretinographic Change after Intravitreal Silicone Oil Injection in Rabbit.

Chang, Kwang; Lee, Jaeheung

Original Article

Journal of the Korean Ophthalmological Society 1988;29(2):279-289.
Published online February 1, 1988.

Electroretinographic Change after Intravitreal Silicone Oil Injection in Rabbit.

Kwang Chang, Jaeheung Lee

Department of Ophthalmology, College of Medicine Seoul National University, Seoul, Korea.

초자체강내 주입돈 실리콘유 (油)가 가토망막전위도에 미치는 영향

장광(Kwang Chang),이재흥(Jae Heung Lee)

Abstract

Effect of silicone oil in vitreous cavity of the rabbit was studied with electroretinogram. Pars plana vitrectomy was performed bilaterally in nine white rabbits, and they were divided into 3 groups. 1.6~1.7 cc of silicone oil was injected in right eye in 1st group, 0.8 cc of silicone oil was injected in right eye in 2 nd group, and 0.8~1.0 cc of silicone oil was injected in right eye after retinal tear was made in 3 rd group. Left eye in each group was used as a control. Photopic and scotopic electroretinographic studies were performed in both eye of rabbits preoperatively and postoperatively 2 days, 1 week, 2 weeks, 3 weeks, and 4 weeks. In each group, a and b-wave amplitude was decreased in silicone oil injected eye compared to control eye at postoperative 2 days, and was increased to normal amplitude at postoperative 4 weeks in both photopic and scotopic electroretinograms. Implicit time of a and b-wave was not affected in each group. Above results suggest that rabbit electroretinogram is not affected by intravitreal silicone oil until postoperative 4 weeks.