The Standardization of Visual Evoked Potential in Pigmented Rabbits.

Bae, Jae Yong; Kim, Si Yeol

Original Article

Journal of the Korean Ophthalmological Society 1988;29(2):309-314.
Published online February 1, 1988.

The Standardization of Visual Evoked Potential in Pigmented Rabbits.

Jae Yong Bae, Si Yeol Kim

Department of Ophthalmology, Kyungpook National University, Taegu, Korea.

유색가토 VEP 의 표준화

배재용(Jae Yong Bae),김시열(Si Yeol Kim)

Abstract

VEP is an objective method for the evaluation of macular function and optic nerve disease, but its large inter and intraindividual variation prevented clinical and experimental application. We recorded a relatively stable VEP A wave in pigmented rabbits with cortical electrode and following results were obtained. The amplitude of VEP A wave was 97.8 +/- 29.8 micro V and latent time was 52.2 +/- 6.9 msec. Inter- and intraindividual variation of VEP latent time was much smaller than that of VEP amplitude. So latent time of VEP A wave may be a good indicator in evaluation of pharmacologic and toxicologic experiment of systemically administered drug.