Journal of the Korean Ophthalmological Society 1978;19(3):265-272.
Published online March 1, 1978.
A Study on the Effect of Hibon in Arteriosclerotic Retinpathy, Diabetic Retinopathy and Cataract.
Ju Pil Kim, Moo Shik Sohn
Department of Ophthalmology, CoIlege of Medicine, Korea University, Korea.
동맥경화성 강막증 , 당뇨병성 강막증 및 백내장에 대한 Hibon 의 치료효과
김주필 , 손무식 ( Joo Pil Kim , Moo Shik Son )
Soon after the discovery of riboflavin, it was recognized that a deficiency of riboflavin was associated with disorders of lid, cornea, lens and retina. This study was devised to observe the effect of riboflavin on the metabolic changes in arteriosclerotic retinopathy, diabetic retinopathy and cataract. The experiment was carried out on 30 adult humans. After each case was treated with riboflavin, visual acuity, retinal change and cholesterol level in serum were determined. The result obtained from this experiment are summarzed as follows; 1. In Arteriosclerotic retinopathy, visual improvement is noted in 46% of 13 cases. Serum cholesterol level is decreased 32mg/dl in average. 2. In diabetic retinopathy, visual improvement is noted in 43% of 14 cases. Serum cholesterol level is slightly increased 0.9mg/dl in average. 3. In cataract, no visual improvement is noted. Serum cholesterol level is decreased 10.2mg/dl in average. 4. There was no known side effect during riboflavin therapy.

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