Cryotherapy on Refractory Fungal Corneal Ulcer: A Case Report.

Kim, Hyun Ju; Lim, Hwa Rang; Koh, Jae Woong

doi:2017.58.10.1194

J Korean Ophthalmol Soc > Volume 58(10); 2017 > Article

Case Report

Journal of the Korean Ophthalmological Society 2017;58(10):1194-1198.
DOI: https://doi.org/10.3341/jkos.2017.58.10.1194 Published online October 15, 2017.

Cryotherapy on Refractory Fungal Corneal Ulcer: A Case Report.

Hyun Ju Kim, Hwa Rang Lim, Jae Woong Koh

Department of Ophthalmology, Chosun University College of Medicine, Gwangju, Korea. ophkoh@hanmail.net

난치진균각막궤양에서 냉동치료 1예

김현주⋅임화랑⋅고재웅

조선대학교 의과대학 안과학교실

Correspondence: Jae Woong Koh,
Email: ophkoh@hanmail.net

Received: 10 August 2017 • Revised: 28 August 2017 • Accepted: 20 September 2017

Abstract

PURPOSE
We report a case of cryotherapy for fungal corneal ulcers that did not respond to antifungal agents. CASE SUMMARY: A 58-year-old man was transferred to our hospital with a left eye corneal ulcer due to pain and visual impairment in his left eye for two weeks, and he was suspected to have a history of fungal infection. At the time of admission, corneal opacity and progressive ulcerative lesions were observed at 5 o'clock in the left eye and visual acuity was 0.025, uncorrected. The corneal ulcer marginal resection, bacterial culture, and potassium hydroxide preparation (KOH) test were performed on lesion sites. Cultures of Candida albicans were reported to grow, topical antibiotics (Fortified tobramycin, Fortified cefazolin, moxifloxacin), and anti-fungal agents (fortified amphotericin B, 0.5%, Natamycin) were administered, but no improvement was observed for 2 weeks. On the 14th day after admission, Cryotherapy was performed. After surgery, eye drops were equally applied, and there was no other discomfort other than pain for 3 days after the operation. He discharged 10 days after surgery, the corneal lesion was healed and the visual acuity was improved to 0.32, uncorrected. CONCLUSIONS: We report a case of cryotherapy for fungal corneal ulcers that did not react with topical antifungal drugs and improved visual acuity and symptom improvement.

Key Words: Cryotherapy;Refractive fungal cornea ulcer