J Korean Ophthalmol Soc > Volume 58(11); 2017 > Article
Journal of the Korean Ophthalmological Society 2017;58(11):1242-1247.
DOI: https://doi.org/10.3341/jkos.2017.58.11.1242    Published online November 15, 2017.
24-hour Ambulatory Blood Pressure in Normal Tension Glaucoma: Associations with Retinal Vessel Diameter and Visual Field Defect Progression.
Aerin Jo, Hyungwoo Lee, Byung Joo Cho
Department of Ophthalmology, Konkuk University School of Medicine, Seoul, Korea. bjcho@kuh.ac.kr
정상 안압 녹내장 환자에서 24시간활동혈압 측정: 망막혈관너비 및 시야결손 진행과의 연관성
조애린⋅이형우⋅조병주
건국대학교 의학전문대학원 안과학교실
Correspondence:  Byung Joo Cho,
Email: bjcho@kuh.ac.kr
Received: 25 May 2017   • Revised: 21 August 2017   • Accepted: 30 October 2017
Abstract
PURPOSE
To investigate the correlation between 24-hour ambulatory blood pressure (BP) monitoring and peripapillary retinal vessel width and visual field (VF) defect progression in normal tension glaucoma (NTG) patients. METHODS: All patients were classified by 24-hour ambulatory BP monitoring as non-dipper (nocturnal dip < 10%) and dipper (nocturnal dip ≥ 10%) group. Vessel diameter, mean deviation (MD) value by VF test and VF progression from Glaucoma Progression Analysis (GPA) were compared among non-dipper and dipper groups. RESULTS: Retinal arterial diameter was wider in the non-dipper group compared to the dipper group (p = 0.015), while retinal venous diameter had no significant relationship between the two groups (p = 0.131). The MD value at baseline and 2 years after was worse in the non-dipper group than the dipper group, respectively (p = 0.006, p = 0.030). But, there was no significant relationship between nocturnal dip and GPA progression (p = 0.658). CONCLUSIONS: There was a statistically significant correlation between nocturnal dips and retinal arterial diameter and MD values. These results suggest that non-invasive fundus photography can predict hemodynamic features like nocturnal dip.
Key Words: Nocturnal dip;Normal tension glaucoma;Retinal vessel;Vessel narrowing;24-hour ambulatory blood pressure monitoring


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