J Korean Ophthalmol Soc > Volume 59(3); 2018 > Article
Journal of the Korean Ophthalmological Society 2018;59(3):246-251.
DOI: https://doi.org/10.3341/jkos.2018.59.3.246    Published online March 15, 2018.
Change in Axial Length in Highly Myopic Adults Using Partial Coherence Interferometry.
Jae Jung Lee, In Ho Lee, Min Won Ahn, Kang Yeun Pak, Sung Who Park, Ik Soo Byon, Ji Eun Lee
1Department of Ophthalmology, Pusan National University School of Medicine, Yangsan, Korea. jlee@pusan.ac.kr
2Medical Research Institute, Pusan National University Hospital, Busan, Korea.
3Department of Ophthalmology, Inje University Haeundae Paik Hospital, Busan, Korea.
4Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.
성인 고도근시안에서 부분결합간섭계를 이용하여 측정한 안축장의 변화
부산대학교 의과대학 안과학교실1, 부산대학교병원 의생명연구원2, 인제대학교 해운대백병원 안과3, 양산부산대학교병원 의생명융합연구소4
Correspondence:  Ji Eun Lee,
Email: jlee@pusan.ac.kr
Received: 6 July 2017   • Revised: 3 January 2018   • Accepted: 19 February 2018
To investigate the change in axial length (AL) in highly myopic adults using partial coherence interferometry, and to identify the factors associated with the increase in AL. METHODS: Medical records of highly myopic adults (≥−6 diopters [D] or AL ≥ 26.0 mm) were retrospectively reviewed. The AL of each patient was measured using partial coherence interferometry at least three times over 2 years, and the yearly change in AL was calculated. Associations between age, AL, choroidal thickness, and the rate of AL change were evaluated using multiple regression analysis. RESULTS: In total, 24 patients (4 males, 20 females) and 44 eyes were included in this study. The mean age was 54.9 ± 10.4 years, the initial AL was 29.335 ± 2.006 mm, the choroidal thickness was 72.7 ± 41.80 µm, the average spherical equivalent was −11.86 ± 3.85 D (−5.1~−22.0 D), and the mean follow-up period was 2.2 ± 0.5 years. A significant increase in AL of ≥0.05 mm was observed in 38 eyes (86.4%) at 2 years. The mean AL was significantly increased, to 29.409 ± 2.007 mm (p < 0.001), at 1 year and to 29.476 ± 2.028 mm (p < 0.001) at 2 years. The average rate of AL change was 0.071 ± 0.049 mm (−0.01~0.19 mm) per year. None of the included factors showed an association with the rate of AL change in multiple regression analysis. CONCLUSIONS: In this study, an increase in AL in highly myopic adults was more frequent than in previous reports using A-scan. Periodic measurements are therefore recommended for the early detection of complications.
Key Words: Axial length;High myopia;Partial coherence interferometry

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