A Case of a Visual Field Defect with Optical Coherence Tomography Changes after Sildenafil Citrate Overdose. |
Hyo Song Park, Jong Yun Yang, Jeihoon Lee |
1Siloam Eye Hospital, Seoul, Korea. genialtoday@naver.com 2The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. |
실데나필 시트르산염 과다복용 후 발생한 시야이상을 동반한 빛간섭단층촬영 변화 |
박효송1,2⋅양종윤1⋅이제훈1 |
실로암안과병원1, 연세대학교 의과대학 안과학교실 시기능개발연구소2 |
Correspondence:
Jeihoon Lee, Email: genialtoday@naver.com |
Received: 9 November 2017 • Revised: 29 December 2017 • Accepted: 19 February 2018 |
Abstract |
PURPOSE A case of a transient visual field defect and a change in spectral-domain optical coherence tomography (SD-OCT) after an overdose of sildenafil citrate is described. CASE SUMMARY: A 67-year-old male with no previous medical history presented with a bluish tinge and visual field defect in both eyes. He had consumed eight tablets of sildenafil citrate (800 mg) 3 days before the visit. His best-corrected visual acuity was 14/20 in the right eye and 20/20 in the left eye. No specific finding was noted on slit-lamp examination. Fundus examination and fundus photography revealed focal foveal hypopigmentation in both eyes. He underwent SD-OCT imaging with the Cirrus HD-OCT (Carl Zeiss Meditec, Oberkochen, Germany), and thickening of the ellipsoid zone and choroid was revealed by SD-OCT scans. He was advised not to take any more sildenafil citrate and was followed for 1 week after the first visit. Central scotomas of both eyes were revealed by a visual field test, and thickening of the ellipsoid zone and choroid remained. His eyes were re-evaluated 1 and 3 months after the first visit, and although the symptoms nearly disappeared, abnormalities in the visual field test and on SD-OCT remained, albeit with some degree of improvement. He revisited us 4 months after the first visit, at which time the visual field test and SD-OCT scans showed results within normal ranges. CONCLUSIONS: Sildenafil citrate overdose can result in a color anomaly (bluish tinge), visual field defects, and thickening of the ellipsoid zone and choroid on SD-OCT scans. |
Key Words:
Color anomaly;Optical coherence tomography;Sildenafil citrate;Visual field defect |
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