| Long-term Recurrence in Neovascular Age-related Macular Degeneration or Polypoidal Choroidal Vasculopathy without First Year Recurrence. |
|
Kee Sun Tae, Jong Woo Kim, Chul Gu Kim, Dong Won Lee, Jae Hui Kim |
1Tae Eye Clinic, Seoul, Korea.
2Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, Korea. kjh7997@daum.net |
| 1년간 재발이 없었던 습성 나이관련황반변성과 결절맥락막혈관병증에서 나타나는 장기 재발 |
|
태기선1⋅김종우2⋅김철구2⋅이동원2⋅김재휘2 |
|
태안과의원1, 건양대학교 의과대학 김안과병원 안과학교실2 |
Correspondence:
Jae Hui Kim,
Email: kjh7997@daum.net
|
|
Received: 17 May 2018 • Revised: 5 July 2018 • Accepted: 27 September 2018 |
| Abstract |
PURPOSE
To investigate the timing and incidence of long-term recurrence in patients with typical neovascular age-related macular degeneration (AMD) or polypoidal choroidal vasculopathy (PCV), in patients with no recurrence during the first year after diagnosis. METHODS: A retrospective review of medical records was performed for typical neovascular AMD or PCV patients with no recurrence during 10 months after three, monthly anti-vascular endothelial growth factor injections. The timing and incidence of recurrence after 10 months were identified. In addition, parameters were compared between the recurrence group and the no recurrence group to identify predictive factors for long-term recurrence. RESULTS: The results were analyzed using 49 eyes from 49 patients, with 19 eyes with typical neovascular AMD and 30 eyes with PCV. Patients were followed-up for a mean period of 32.3 ± 9.3 months after three loading injections. Recurrence was noted in 20 eyes (40.8%) at a mean of 22.6 ± 9.4 months after the third anti-vascular endothelial growth factor injection. The timing of recurrence was as follows: 13 eyes at ≥ 12 months and < 24 months, four eyes at ≥ 24 months and < 36 months, and three eyes at ≥ 36 months. When comparing the recurrence and no-recurrence groups, the follow-up period was significantly longer in the recurrence group (p = 0.003). However, there was no other factors that were significantly associated with recurrence. CONCLUSIONS: Long-term recurrence occurred in 40.8% of the cases when there was no recurrence during the first year after diagnosis. No factors predictive of recurrence were found. These results imply the importance of long-term and continuous follow-up examination of all patients. |
| Key Words:
Age-related macular degeneration;Anti-vascular endothelial growth factor;Polypoidal choroidal vasculopathy;Recurrence |
|
PDF Links
Full text via DOI
Download Citation
