A Case of Conjunctival Mass with Infectious Mononucleosis by EBV.

Shin, Kyoung Yoon; Chang, Moo Hwan; Kyung, Sung Eun

doi:2014.55.10.1554

J Korean Ophthalmol Soc > Volume 55(10); 2014 > Article

Case Report

Journal of the Korean Ophthalmological Society 2014;55(10):1554-1557.
DOI: https://doi.org/10.3341/jkos.2014.55.10.1554 Published online October 15, 2014.

A Case of Conjunctival Mass with Infectious Mononucleosis by EBV.

Kyoung Yoon Shin, Moo Hwan Chang, Sung Eun Kyung

Department of Ophthalmology, Dankook University Medical College, Cheonan, Korea. kseeye@hanmail.net

결막 임파종으로 의심된 환자에서 확진된 엡스타인-바 바이러스 결막종물 1예

신경윤⋅장무환⋅경성은

Department of Ophthalmology, Dankook University Medical College, Cheonan, Korea

Abstract

PURPOSE
To report a case of conjunctival mass with infectious mononucleosis by Epstein-Barr virus (EBV) confirmed with Epstein-Barr encoding region (EBER) in situ hybridization. CASE SUMMARY: A 8 year-old male without underlying disease was referred with counjunctival mass on the right eye starting 3 days ago. In ophthalmologic evaluation, there was injected, nontender, and "salmon patch" appearance conjunctival lesion on right superior bulbar conjunctiva. The patient was admitted to pediatrics with sore throat and fever. The tonsil were enlarged and white blood cell count was 14960/uL. EBV polymerase chain reaction (PCR) test and Viral capsid antigen Immunoglobulin M (VAC IgM) test were positive, the diagnose of infectious mononucleosis by EBV was made. After 5 days steroid eyedrop therapy, biopsy was performed because the lesion was not improved. There were lymphocyte infiltration, chronic inflammation and positive in EBER in situ hybridization. CONCLUSIONS: Elevated and pinkish lesion on conjunctiva, EBV lesion should be considered as differential diagnosis.

Key Words: Conjunctival mass;Infectious mononucleosis