| A Case of Lymphomatoid Papulosis of the Eyelid. |
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Youn Joo Choi, Hyun Chul Jin, Nam Ju Kim, Ho Kyung Choung, Sang In Khwarg |
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. khwarg@snu.ac.kr
2Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.
3Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea.
4Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea. |
| 눈꺼풀에 발생한 림프종모양 구진증 1예 |
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최연주1⋅진현철1⋅김남주2⋅정호경3⋅곽상인1,4 |
Department of Ophthalmology, Seoul National University College of Medicine1, Seoul, Korea
Department of Ophthalmology, Seoul National University Bundang Hospital2, Seongnam, Korea
Department of Ophthalmology, Seoul National University Boramae Hospital3, Seoul, Korea
Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute4, Seoul, Korea |
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| Abstract |
PURPOSE
Lymphomatoid papulosis (LyP) is one of the primary cutaneous CD30-positive lymphoproliferative disorders. LyP of the eyelid has rarely been reported. Herein, a case of typical LyP of the medial canthal area is reported. In addition, a literature review was performed. CASE SUMMARY: A 40-year-old female presented with a skin mass in the medial canthal area of the left eye that developed 2 months earlier. Initially, a focal skin lesion developed, and even with conservative treatment at a local clinic, progressed to a mass lesion having a central ulceration and adjacent edema. After 6 weeks, the adjacent edema had gradually decreased. On ophthalmic examination, the left medial canthal lesion was a 6 x 6 mm sized elevated mass with a central crater covered by crust. The clinical impression was keratoacanthoma. The lesion was widely excised and reconstructed by a full-thickness skin graft after an incisional biopsy. Histopathologic findings showed dermal infiltration of various inflammatory cells with atypical lymphocytes showing positivity to the CD30 antigen, and LyP was diagnosed. Systemic evaluation showed no evidence of systemic lymphoma and the patient has remained free of recurrence or systemic disease after a 1-year follow-up. |
| Key Words:
CD30 lymphoproliferative disease;Eyelid;Lymphomatoid papulosis |
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