| Effect of 0.1% Sodium Hyaluronate and 0.05% Cyclosporine on Tear Film Parameters after Cataract Surgery. |
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Won Choi, Kyung Chul Yoon |
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Department of Ophthalmology, Chonnam National University Medical School, Gwangju, Korea. kcyoon@chonnam.ac.kr |
| 백내장 수술 후 0.1% 히알우론산과 0.05% 사이클로스포린 A가 눈물막에 미치는 효과 |
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최 원⋅윤경철 |
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Department of Ophthalmology, Chonnam National University Medical School, Gwang-ju, Korea |
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| Abstract |
PURPOSE
To evaluate the efficacy of topical 0.1% sodium hyaluronate (HA) and 0.05% cyclosporine A (CsA) on tear film parameters after cataract surgery. METHODS: A total of 109 eyes of 86 patients who underwent cataract surgery were divided into four groups: 74 eyes without dry eye syndrome (groups 1 and 2) and 35 eyes with dry eye syndrome (groups 3 and 4). Groups 1 (37 eyes) and 3 (17 eyes) used 0.1% HA only, while Groups 2 (37 eyes) and 4 (18 eyes) used both 0.1% HA and 0.05% CsA. Tear film break-up time (BUT), Schirmer's test, tear clearance rate (TCR) and keratoepitheliopathy were evaluated before surgery and 1 week, 1 month, 2, 3 and 6 months after surgery. RESULTS: But, Schirmer's test and TCR recovered at postoperative 3 months in groups 1 and 3, after 2 months in group 2 and after 1 month in group 4. Keratoepitheliopathy recovered at postoperative 1 month in groups 1, 2 and 4, after 2 months in group 3. CONCLUSIONS: The combined use of topical 0.1% HA with 0.05% CsA is helpful in restoring tear film parameters after cataract surgery especially in patients with dry eye syndrome. |
| Key Words:
Cataract operation;Cyclosporine;Sodium hyaluronate;Tear film parameters |
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