J Korean Ophthalmol Soc > Volume 53(1); 2012 > Article
Journal of the Korean Ophthalmological Society 2012;53(1):87-93.
DOI: https://doi.org/10.3341/jkos.2012.53.1.87    Published online January 15, 2012.
Comparison of Choroidal Thickness in Eyes with Central Serous Chorioretinopathy, Asymptomatic Fellow Eyes and Normal Eyes.
Joon Hee Cho, So Hyun Bae, Jae Ryong Han, Woo Ho Nam, Ha Kyoung Kim
1Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. ophkim@hallym.or.kr
2Department of Ophthalmology, Hangang Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
중심장액맥락망막병증 환자의 이환된 눈과 무증상 반대편 눈, 정상 대조군과의 맥락막두께 비교
조준희1⋅배소현1⋅한재룡2⋅남우호1⋅김하경1
Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine1, Seoul, Korea Department of Ophthalmology, Hangang Sacred Heart Hospital, Hallym University College of Medicine2, Seoul, Korea
Abstract
PURPOSE
To compare the choroidal thickness in central serous chorioretiopathy (CSC) patients and normal controls using spectral domain optical coherence tomography (SD-OCT). METHODS: The authors compared the choroidal thickness in eyes with CSC, fellow eyes and in normal eyes. In addition, the authors attempted to determine any correlation between choroidal thickness and other factors such as age, height of serous retinal detachment, and spherical equivalent. Choroidal thickness was measured using a perpendicular line from the outer margin of the subfoveal retinal pigment epithelium to the inner surface of the sclera. RESULTS: Twenty-five eyes of 25 CSC patients, 17 fellow eyes and 29 age-matched normal eyes were examined and categorized as group 1, group 2 and group 3, respectively. Subfoveal choroidal thickness was 370.64 +/- 58.06 microm in group 1, 301.85 +/- 47.83 microm in group 2, and 261.84 +/- 48.22 microm in group 3. The choroidal thickness in group 1 was significantly greater than those in group 2 and group 3, and the choroidal thickness in group 2 was significantly greater than that in group 3 (p = 0.001, p < 0.001, p = 0.004, respectively), where the choroidal thickness showed a negative correlation with age (p = 0.015). CONCLUSIONS: The choroidal thickness was greater in eyes with CSC and in their fellow eyes compared to that in normal eyes. The results suggest that CSC may be caused by choroidal vascular hyperpermeability and increased hydrostatic pressure in the choroid.
Key Words: Central serous chorioretinopathy;Choroidal thickness;Spectral domain optical coherence tomography


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