The Effects of Cheap Tinted Contact Lenses on Corneal Swelling and Ocular Surface Inflammation. |
Jong Suk Song, Hwa Lee, Jung Wan Kim, Mun Hee Chang, Suk Kyu Ha, Hyo Myung Kim |
Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea. crisim@korea.ac.kr |
국내의 저가 컬러 콘택트렌즈가 각막 부종 및 안구 표면 염증에 미치는 영향 |
송종석ㆍ이 화ㆍ김정완ㆍ장문희ㆍ하석규ㆍ김효명 |
Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea |
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Abstract |
PURPOSE To evaluate the effects of cheap tinted contact lenses on corneal swelling and ocular surface inflammation, compared to hydrogel and silicone hydrogel contact lenses. METHODS: Forty eyes of 20 New Zealand white rabbits were randomly assigned to 4 groups. Two types of tinted contact lenses, hydrogel lenses, and silicone hydrogel lenses were each applied to 10 rabbit eyes. Corneal thickness and tear lactate dehydrogenase (LDH) activity were measured at 1 and 4 days after contact lens wear, and the inflammation of ocular surface was scored at 4 days after contact lens wear. The internal surface of the cheap tinted lens was examined with a scanning electron microscope to compare the surface quality between the tinted and non-tinted area. RESULTS: Although the corneal swelling of the silicone hydrogel lens group was significantly lower than the other 3 lens groups after contact lens wear (p<0.01), the common hydrogel lens group was not different from the 2 tinted contact lens groups (p>0.1). Tear LDH activity at 1 and 4 days after contact lens wear showed no significant difference among the 4 groups (p>0.29). The scores of ocular surface inflammation in the 2 tinted contact lens groups were greater than the hydrogel and silicone hydrogel lens groups (p=0.03). The scanning electron microscope revealed the internal surface of the tinted area in the tinted contact lens was coarse and irregular though the surface of the non-tinted area was relatively smooth. CONCLUSIONS: Regarding corneal swelling and tear LDH activity, the cheap tinted contact lenses used in Korea were not significantly different from the common hydrogel contact lenses. However, tinted contact lenses showed a greater tendency to provoke ocular surface inflammation than other lenses. The coarse and irregular surface of the tinted area in the tinted contact lens appears to play a role in provoking severe ocular surface inflammation. |
Key Words:
Corneal swelling;Lactate dehydrogenase;Ocular surface inflammation;Scanning electron microscope;Tinted contact lens |
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