Retinal Nerve Fiber Layer Thickness in Children With Glaucoma. |
Kui Dong Kang, Aman Shah Abdul Majid, Yeon Deok Kim, Jee hyun Kwag, Hye Bin Yim |
1Department of Ophthalmology, Oxford Eye Hospital, Headington, Oxford, UK. 2Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, UK. 3Advanced Medical and DentalInstitute, Universiti Sains Malaysia, Penang, Malaysia. 4Hangil Eye Hospital, Incheon, Korea. 5Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. 6Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, Korea. yimhb@catholic.ac.kr |
소아에서 빛간섭단층촬영을 통하여 얻어진 지표를 이용한 녹내장의 판별 |
강규동1,2ㆍAman Shah B. Abdul Majid2,3ㆍ김연덕4ㆍ곽지현5ㆍ임혜빈6 |
Department of Ophthalmology, Oxford Eye Hospital, Headington1, Oxford, UK / Nuffield Laboratory of Ophthalmology, University of Oxford2, Oxford, UK / Advanced Medical and DentalInstitute, Universiti Sains Malaysia3, Penang, Malaysia / Hangil Eye Hospital4, Incheon, Korea / Department of Physiology, Anatomy and Genetics, University of Oxford5, Oxford, UK /Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Incheon St. Mary’s Hospital6, Incheon, Korea |
|
Abstract |
PURPOSE To find the optimal parameter of retinal nerve fiber layer (RNFL) analysis in optical coherence tomography (OCT) for diagnosing glaucoma in children. METHODS: The study was comprised of 127 eyes of 84 patients (aged 6 to 18 years) who visited our institute between March 2006 and February 2008. Subjects were classified into normal, glaucoma suspect and glaucoma groups, and each eye was scanned using Stratus 3.0 OCT. Routine ophthalmic examinations including fundus examination, visual field test and OCT RNFL analysis were performed. RESULTS: There were 55 normal eyes, 27 glaucoma suspect eyes and 45 glaucomatous eyes. The average RNFL thickness was the most useful parameter to differentiate between the glaucoma and non-glaucoma groups. The next most useful parameter was inferior average thickness, followed by superior RNFL thickness. The sensitivity and specificity of the new discriminant of the formula used were 78%, and 68.6%, respectively. CONCLUSIONS: In OCT analysis, the average RNFL thickness is the most useful parameter in the diagnosis of glaucoma in children. The new discriminant of the formula is useful in the diagnosis of pediatric glaucoma patients. |
Key Words:
Children;Optical coherence tomography;Retinal nerve fiber layer analysis |
|